Angel Gabriel is talking to Mary saying that God has chosen you, made you pure and holy, reserved for His work.
She was chosen to be above all women of the world including Mohammad,s wifes who are kept so dear in the minds of most Muslims.

Therefore, Mary's position is highly upheld and respected by all Muslims according to the above verse.

"3.43":    O Marium! keep to obedience to your Lord and humble yourself, and bow down with those who bow.

Mary was reminded to exercise the greatest commandment as a sign of God's expectation, as all other prophets of God had done so in humility.
1) To love is to obey, 2) Obedience is better than sacrifice.

"3.44":    This is of the announcements relating to the unseen which We reveal to you; and you were not with them when they cast their pens (to decide) which of them should have Marium in his charge, and you were not with them when they contended one with another.

This is an argument or excitement, which took place in heaven among the angels.

For that reason they were casting lots among themselves. Is it silly? Maybe, but it is recorded in their book to show that Mohammad has insight about heaven so when Quran talks about heaven in other places it makes it more of the same revelation


"3.45":    When the angels said: O Marium, surely Allah gives you good news with a Word from Him (of one) whose name is the 'Messiah', Isa son of Marium, worthy of regard in this world and the hereafter and of those who are made near (to Allah).

(Remember) when the angels said: "O Maryam (Mary)! Verily, Allah gives you the glad tidings of a Word ("Be!" - and he was! i.e. Iesa (Jesus) the son of Maryam (Mary)) from Him, his name will be the Messiah Iesa (Jesus), the son of Maryam (Mary), held in honour in this world and in the Hereafter, and will be one of those who are near to Allah."  (Chapter #3, Verse #45) from another translation.

Here is what I see from this passage.
1) The good news is about a "Word" Notice the capital letter in Word meaning different from a "word" and is refering to someone who has a name.
2) The good news is about a "Word" and his name is Jesus
3) He will be Messiah (Christ) {in Hebrew and in Greek} Jesus meaning Jehovah Saves
4) He is worthy of regard (very high) in this world and hereafter.
Every knee shall bow in heaven and on earth and under the earth that He (Jesus) is Lord.

I see two areas of confusions:
1) Muslims equals Jesus with other prophets of God and say: Jesus will be one of those who are near to God.
2) they add son of Maryam to Jesus to point to him as flesh and blood and not Deity.

I must point this fact out that every prophet or messenger of God could not say anything or perform any miracles on their own unless God has instructed them including Moses one of the greatest prophet of God. Jesus on the other hand, having full authority and power, knowing the will of His Father, talked with authority and power and performed miracles without the need of checking with the Father. He is the only one that did something for mankind (paid the penalty of sin, Grace) while every other prophets of God demanded something from mankind (Law).